Table II. Production of IL-6, TNF-α, and IFN-α by human pDCs after overnight incubation with IL-3, R848, or the different Ab-coated NPs
IL-6 (pg/ml)TNF-α (pg/ml)IFN-α (pg/ml)
IL-3447 ± 69564 ± 12411 ± 4
R8485999 ± 28574287 ± 1358773 ± 295
Anti–DC-SIGN–NP1514 ± 605860 ± 336332 ± 167
Anti–DEC-205–NP2948 ± 5854036 ± 1541736 ± 276
Anti–DCIR-NP3270 ± 9043429 ± 1220661 ± 275
Anti–BDCA-2–NP4276 ± 16123776 ± 1137712 ± 285
Anti–CD32-NP5186 ± 20123824 ± 1034721 ± 279
  • Data are shown as mean ± SEM.