Table I. Overview of human CD34+ HSC donors used for transplantation of NSG and NSG-A2/DR1 mice
HSC DonorHLA TypeType and No. of Mice TransplantedLevel of Human Cell Reconstitution: Percent Human CD45 (Mean ± SEM)Level of Antiviral Immunity: Photons/s at Day 10 Postinfection (Mean ± SEM)
1A2+DR1+NSG0
NSG-A2/DR1441.3 ± 4.62.3e7 ± 9.9e6
2A2+DR1NSG352.2 ± 6.25.6e7 ± 1.6e7
NSG-A2/DR1553.8 ± 1.72.3e7 ± 5.7e6
3A2-DR1NSG661.2 ± 2.25.1e7 ± 1.5e7
NSG-A2/DR10
4A2+DR1+NSG0
NSG-A2/DR11860.1 ± 5.32.4e7 ± 7.1e6
5A2-DR1NSG1154.1 ± 4.48.6e7 ± 2.2e7
NSG-A2/DR10