Table III. Summary of downregulated microRNAs in SSc dermal fibroblasts by a microarray analysis
Gene NameFold Change
miR-10a<0.01
miR-142-3p<0.01
miR-146a<0.01
miR-196a<0.01
miR-2060.05
miR-1850.05
miR-146b-5p0.07
miR-208a0.09
miR-1920.10
miR-15b0.13
let-7c0.13
miR-1950.16
miR-1260.16
miR-1240.18
miR-160.18
miR-99a0.20
miR-2100.20
miR-3700.20
miR-1000.21
miR-1280.22
miR-129-5p0.22
miR-4880.23
miR-930.24
miR-125a-5p0.25
miR-210.28
miR-142-5p0.28
miR-10b0.28
miR-1550.28
let-7a0.32
miR-170.32
let-7g0.33
  • A mixture of equal amounts of microRNAs from five normal fibroblasts or five SSc fibroblasts was prepared, and microRNA expression profile in each cell type was evaluated using PCR array. The raw Ct was normalized using the mean value of four housekeeping genes. Fold-change (1/2the raw Ct of each microRNA − Ct of small RNA housekeeping genes) is shown.