Table I. sIgM+ frequencies and numbers in SPLs of SW, BAFFR−/−, NF-κB1−/−, and xid mice and their respective controls, SW, B6, WT, and CBA, at the indicated ages
StrainsAgenasIgM+ Cell Frequency ± SD (%)sIgM+ Cells × 106 ± SD
SWNeonates3 db1219.50.9
8 db733.110.0
12 db333.018.8
17 d453.9 ± 1.332.7 ± 3.0
21 d835.4 ± 4.726.1 ± 4.4
Adults5 wk544.7 ± 1.940.4 ± 8.6
BAFFR−/−Neonates5 db56.741.1
7 db517.45.2
10 db328.97.9
Adults11 wk25.6 ± 2.93.5 ± 0.9
NF-κB1−/−Neonates6 db319.81.1
9 db517.61.6
12 db543.45.1
Adults8 wk222.1 ± 8.123.8 ± 7.2
xidNeonates10 d935.05.8
Adults12 wk215.9 ± 0.97.2 ± 2.0
B6Adults10 wk337.3 ± 1.928.1 ± 2.9
WTAdults8 wk338.0 ± 3.439.6 ± 15.2
CBAAdults12 wk231.2 ± 7.620.4 ± 3.8
  • a Number of animals.

  • b Neonate SPLs were pooled for immunofluorescence analyses; values provided for older animals indicate average ± SD.