Table IV. ImmGen T versus B differential signature genes
B CellsT Cells
Gene SymbolFollicular Peritoneal CavityFollicular SpleenBone Marrow Fraction FMarginal Zone SpleenT3 SpleenCD19 SpleenCD19 SpleenCD4 SpleenCD4 SpleenCD4 Memory SpleenCD4 Naive Lymph NodeCD4 Naive SpleenCD4 Naive ThymusCD8 Naive Mesenteric Lymph NodeCD8 Naive SpleenAverage FC B Versus Tt Test p Value B Versus T
Cd3g42474857595939482653825933545949466261587552490.00911.55 × 10−13
prkch51474349414539231725232840213518242578286721620.01871.10 × 10−10
Fyb2825393530442419182463207914241006131416919910.02011.11 × 10−6
Prkcq47434460453846275628622056236519512188219419580.02021.22 × 10−10
Tcf71047192871198971361145152959441940514272414936060.02292.19 × 10−11
ll7r45384645395734243125861797187615641432164515170.02332.25 × 10−8
ltk89718185718866351539672359356027753221364429660.02432.81 × 10−10
Cd964138343535453311621684189013557831612207211040.02564.36 × 10−7
Ms4a4b353537313944331274162716311267921111614559470.02841.11 × 10−8
Cd3d69626253536046163713001704198513392022153514050.03576.66 × 10−10
Themis452832333835311237142881689463769111327100.03667.12 × 10−7
Lcp270578270687960176122782487163713211744185812700.03883.25 × 10−8
Thy1163119136132146109126216427703308360631693341416539520.04023.06 × 10−9
Slfn177629660706959153115801386237819962516133112080.04043.13 × 10−7
Lat10796109951019185275922302003233719812538230117960.04365.96 × 10−11
Cd3e1061011101041008289150918752152228222022437235122690.04637.19 × 10−11
Emb7926104188195662139218041170158313161359167511430.05338.13 × 10−10
Skap165807585637968139415521345137812171309137410350.05554.88 × 10−12
Actn1939914611310416116421412402963233422052207241121460.05982.54 × 10−8
Txk77849283808686159815891136152612791395150911880.05992.78 × 10−11
Camk4333740314043337817396355735086024774080.06211.58 × 10−8
Apol7e4951505445394841167356882353998612726930.06437.59 × 10−6
Cd69889101728363721128123315171350128716469959620.06533.39 × 10−9
H2-Eb1440455675931592358225021601513114114315214212914817538.10284.42 × 10−12
Ebf11654213815251610169013942251453633495839366039.45102.86 × 10−9
Cd22353347854131439653603507513584123216879786939939.88249.48 × 10−10
Kmo1084136612511075187212901597332630284531383940.53341.61 × 10−8
Faim33656442541573211593740074470989111281121828711243.62349.21 × 10−9
Lrrk22620236021952015197917622500434343455246525546.38689.68 × 10−11
Cd1801294279020543633279320163434515048496545596048.29062.26 × 10−6
lgk1289196914291284139612101737322424354024243849.21194.00 × 10−9
Cd192630261526902918308424783043454552507548526651.28281.58 × 10−13
H2-DMb23814447743394410418945204545737999797391857652.75241.78 × 10−15
Rasgrp31289226717821062203114712135322729324031284152.99392.36 × 10−7
Pax543214312424336965143425352375581718494947610154.34163.34 × 10−8
Cd79a65936616778156617289556261389910510513112110511716555.05042.39 × 10−11
Lyn2265272525382978275026442928363184644143334657.00733.56 × 10−13
Ly861773257820883852233831703130494242455948435057.06892.39 × 10−7
Ebf12438247621992291256120582667342930394534324466.57123.09 × 10−13
Bank13567420234933483363331044467414051455949446176.16732.42 × 10−11
Scd13163394739873679384330733637443637345547425183.84591.46 × 10−12
Cd74892989999023788795596753827970802088594127575986.98934.71 × 10−12
H2-Ab151356548660060916837406063506746426255574666108.21058.45 × 10−10
Ms4a132354144339353874218365948613625243125242135149.27433.72 × 10−9
H2-Aa58996380700764016485474765024328283545323231180.55297.57 × 10−12
  • Expression value, population FC value (defined as the average FC between all B and T populations above), and p values (Student t test) for these FC are shown for the top 25 most differentially expressed genes for T and B populations. All cell types were profiled on the Affymetrix 1.0 ST array.