Table III. Fecal blood of CD4+CD45RBhigh cell-induced colitis is cured by cotransfer of in vitro-activated CD8+CD122+ cells
Weeks after T Cell Transfer
Transferred Cells3456789101112
No cells0/40/40/40/40/40940/40/40/40/4
4+45RBhigh alone0/42/44/44/44/44/44/44/44/44/4
4+45RBhigh and 8+122+ (naive)0/41/42/43/43/44/44/44/44/44/4
4+45RBhigh and 8+122+ (activated)0/42/43/44/43/42/40/40/40/40/4
4+45RBhigh and 4+25+0/43/44/43/42/41/40/40/40/40/4
  • Rag-2−/− mice that received 4 × 105 CD4+CD45RBhigh cells at week 0 further received 2 × 105 of indicated cells at week 4. Fecal blood was checked every week. Data indicate fecal blood-positive mice in total mice used for each experimental group.