Table II. Fecal blood of CD4+CD45RBhigh cell-induced colitis is only partially prevented by cotransfer of IL-10–deficient CD8+CD122+ cells
Weeks after T Cell Transfer
Transferred Cells3456789101112
No cells0/40/40/40/40/40/40/40/40/40/4
4+45RBhigh alone0/41/44/44/44/44/44/44/44/44/4
4+45RBhigh and 8+122+ (WT)0/40/40/40/40/40/40/40/40/40/4
4+45RBhigh and 8+122 (IL-10−/−)0/40/40/41/42/43/44/44/44/44/4
4+45RBhigh and 4+45RBlow0/40/40/40/40/40/40/40/40/40/4
  • Rag-2−/− mice that received 4 × 105 CD4+CD45RBhigh cells with/without 2 × 105 of indicated cells obtained from wild-type (WT) mice or IL-10−/− mice were analyzed for their fecal blood every week. Data indicate fecal blood-positive mice in total mice used for each experimental group.