Gene | Oligonucleotide Sequence^{a} | rag1/gh Ratio^{b} | p Value^{c} | gh Area (a.u.)^{d} | p Value^{c} |
---|---|---|---|---|---|

None | 2.38 ± 0.13 (n = 22) | 1.000 ± 0.038 | |||

il7r | 5′-AGATAATCCACAAAAGTCCCGCCAT-3′ | 1.17 ± 0.09 (n = 25) | <0.001 | 1.102 ± 0.035 | 0.14 |

jak3 | 5′-ACGGCACCTCTTCCTCTTCACTCAT-3′ | 1.55 ± 0.08 (n = 29) | <0.001 | 0.938 ± 0.027 | 0.55 |

jak1 | 5′-TCCATGACTGCTAGTTCTGGCATCC-3′ | 1.46 ± 0.20 (n = 11) | <0.001 | 0.905 ± 0.043 | 0.32 |

↵

Antisense orientation.^{a}↵

Mean ± SEM; the number of embryos (^{b}*n*) analyzed is shown in parentheses.↵

Significance level relative to control; unequal variances^{c}*t*test, with Bonferroni correction for mutliple testing, two-tailed.↵

Size of the hypophysis as determined by hybridization signal of^{d}*gh*gene is given in arbitrary units (a.u.); means ± SEM.