Table I.

Characteristics of the study population

CharacteristicsCohort 1Cohort 2Whole Populationa
No. subjects252567
Age (2.2–15.6 years) (mean ± SEM)7.3 ± 0.76.7 ± 0.67.3 ± 0.4
Male/female15/1013/1240/27
% Atopic95.096.096.8
% Virally infected85.082.480.0c
Severity scoreb (5–15) (mean ± SEM)11.6 ± 0.211.3 ± 0.410.3 ± 0.3
  • a Ninety-six percent of the subjects had a previous diagnosis of asthma.

  • b National Institutes of Health severity scoring system.

  • c Rhinovirus was isolated in 95.0% of these virally infected subjects; 16.3% had other viruses (enterovirus, bocavirus, influenza, parainfluenza, human metapneumovirus, respiratory syncytial virus, and coronavirus). There were 10 dual infections and 2 triple infections, with HRV present in all of these cases.