Table II.

Malaria outcomes over the 8-mo study period, by age group

Age Group, YearsAll (n = 87)
2–4 (n = 35)5–7 (n = 11)8–10 (n = 25)18–25 (n = 16)
Malaria incidence, mean (±SD), no. of episodesa2.11 (±1.25)2.09 (±0.83)1.00 (±1.22)0.12 (±0.40)1.44 (±1.32)
Severe malaria, no. of episodesb30003
At least one malaria episode, % (no.)88.6 (31)100.0 (11)56.0 (14)18.8 (3)67.8 (59)
Time to first malaria episode, days since enrollment (median)c108128155242136
Parasitemia at first malaria episode, parasites/μl (geometric mean (95% CI))40,457 (28,026–58,404)10,810 (1,293–90,407)11,697 (4,618–29,630)6,949 (5,329–9,062)20,586 (13,157–32,211)
  • a Malaria episode defined as temperature > 37.5°C, asexual parasitemia > 5000/μl, and nonfocal physical examination.

  • b World Health Organization definition of severe malaria (1).

  • c All study participants were enrolled during a 2-wk period just prior to the 6-mo malaria season.