Table I.

Summary of pilot trials of PMX205 treatment

Trial No.No. Animals Untreated/TreatedAge (mo)PMX205 (μg/ml, drinking water)PMX205 (mg/kg, s.c.)Treatment Length (wk)% Decrease (PMX treated from untreated)
ThioflavineTotal amyloidCD45GFAP
1a5/311–1410123334155
1b5/811–141011259a51b49c40
2a5/311–1320862b69c68b48c
2b5/411–13201846c5448c44c
  • a p < 0.001;

  • b p < 0.01;

  • c p < 0.05.