Table II.

Transfer of secondary MOG-specific Th1 and Th17 cells into C57BL/6 recipients

Clinical DiseaseHistological Diseasea
IncidenceMortalityMean Day of OnsetbMean Max. ScorebNo. Lesions in MeningesNo. Lesions in ParenchymaTotal No. Lesions
2°Th17/70/712.1 ± 3.32.9 ± 0.538 ± 1161 ± 2399 ± 26
2°Th17 + IL-29/116/1114.0 ± 2.14.4 ± 0.959 ± 2491 ± 33150 ± 54
2°Th17 + IL-236/102/1013.5 ± 3.63.6 ± 1.183 ± 14112 ± 13195 ± 21
  • a Averages were calculated only from mice that developed clinical signs of EAE and survived.

  • b Averages calculated only from mice that developed clinical signs of EAE.