Table I.

Transfer of primary MOG-specific Th1 and Th17 cells into C57Bl/6 recipients

Clinical DiseaseHistological Diseasea
IncidenceMortalityMean Day of OnsetaMean Max. ScoreaNo. Lesions in MeningesNo. Lesions in ParenchymaTotal No. Lesions
1°Th10/50/5N/AN/AN/AN/AN/A
1°Th17 plus IL-233/50/537.7 ± 3.83.2 ± 1.069 ± 42121 ± 59190 ± 101
  • a Averages calculated only from mice that developed clinical signs of EAE. N/A indicates not applicable.