Table I.

Affinity of LPS to its receptors and soluble binding proteins

ImmobilizedLPS KD (M)aRefs.
CRISPLD22.46 ± 0.8 × 10−6Fig. 1D
CRISPLD21.33 ± 0.9 × 10−6Fig. 1Bb
LBP1.40 × 10−88
CD140.98 × 10−58
CD140.87 ± 0.2 × 10−532
MD-22.33 ± 0.9 × 10−632
TLR41.41 ± 0.7 × 10−532
  • a All KD values were measured by SPR assay.

  • b Data from three independent experiments (mean ± SD).