Percentages of NK cell subsets expressing self-MHC class I-specific inhibitory receptors in B6 micea
| No Preactivation | Poly(I:C) (preactivation) | |||
|---|---|---|---|---|
| Observedb | Predictedb | Observed | Predicted | |
| C+I+NKG2+ | 7.7 ± 0.6c | 9.0 ± 0.5 | 7.6 ± 1.0 | 8.6 ± 1.5 |
| C+I+NKG2− | 11.1 ± 0.6 | 12.0 ± 0.7 | 9.2 ± 1.6 | 9.6 ± 1.5 |
| C−I+NKG2+ | 17.4 ± 1.0 | 15.0 ± 1.0 | 18.4 ± 2.4 | 17.5 ± 1.8 |
| C+I−NKG2+ | 6.5 ± 0.6 | 7.1 ± 0.5 | 6.7 ± 1.2 | 6.8 ± 0.8 |
| C−I+NKG2− | 17.4 ± 1.0 | 20.0 ± 0.9 | 20.2 ± 1.1 | 19.7 ± 1.3 |
| C+I−NKG2− | 12.1 ± 0.8 | 9.4 ± 0.8 | 9.1 ± 1.3 | 7.7 ± 1.1 |
| C−I−NKG2+ | 11.2 ± 0.7 | 11.8 ± 0.6 | 14.3 ± 2.5 | 14.1 ± 1.8 |
| C−I−NKG2− | 15.7 ± 0.8 | 14.2 ± 0.9 | 14.5 ± 2.5 | 16.0 ± 2.7 |
a NK cells expressing any combinations of two or three self-MHC class I-specific inhibitory receptors in spleens from B6 mice previously treated or not with poly(I:C).
b Observed percentages are compared to those predicted by the product rule, which predicts percentages of cells expressing a combination of receptors by multiplying the percentages of cells expressing or not each receptor. For example, the predicted percentage of C+I−NKG2+ cells equals (%C+)(%I−)(%NKG2+)/10,000.
c Numbers represent percentages of NKp46+ NK cells (mean ± SD; n = 5).