Table IV.

Significant partial rank correlations between parameters identified in the Sensitivity Analysis in Fig. 4 and various granuloma outcome measures 20 and 200 days postinfection for several different outcome variables (column 1)a

αBiαBesTNFTmove
Day 20Day 200Day 20Day 200Day 20Day 200Day 20Day 200
Outcome measure
 Be+++++++
 Bi+++
Total T cells
 Tγ
Secretor Tγb+++
 Tc
 Treg
Total Macs
 Mr
 MI
 Mci++++
 Ma++
TNF+
Chemokines++
Caseation+++
Be growth rate++++++
Granuloma sizeNDcNDcNDcNDc
  • a Parameter definitions are given in Tables I–III. Significant positive correlations: +++, p < 0.0001; ++, p < 0.001; +, p < 0.01. Significant negative correlations: − − −, p < 0.0001; − −, p < 0.001; -, p < 0.01.

  • b Number of Tγ cells actively secreting IFN-γ.

  • c ND, Not done due to relative lack of granuloma formation by day 20.