Table V.

Serum cytokine profile between fatal and recovered SARSa

Fatal SARSRecovered SARSp
Patients (n)1187
Th1 cytokines (pg/ml)
 IFN-γ22.4 ± 8.028.2 ± 6.50NS
 IL-20.92 ± 0.300.87 ± 0.20NS
 TNF-α1.85 ± 0.331.24 ± 0.53NS
 IL-126.33 ± 2.2919.4 ± 9.83NS
Th2 cytokines (pg/ml)
 IL-46.63 ± 0.843.42 ± 0.66<0.001
 IL-52.81 ± 0.970.64 ± 0.120.04
 IL-1013.2 ± 5.169.05 ± 1.970.05
Inflammatory cytokines (pg/ml)
 IL-19.01 ± 2.0929.4 ± 8.410.04
 IL-627.7 ± 11.947.7 ± 8.99NS
 IL-8159.7 ± 11648.8 ± 7.150.03
  • a Recovered and fatal SARS groups were described using the geometric mean ratio and 95% confidence intervals. ANOVA with age as a covariate (ANCOVA) was used for comparisons of variables between groups of patients. Unequal variances were taken into account by the t test for comparison of two samples.