Table IA.

(Continued)

QTLLODMarkersSearch Region (bp)RAA Genes within QTLRAAP Genes within QTL
Cia12 (14)4.6ΔD12Wox5 (0bp)-D12Arb60–36,819,134Flt1 (Vegfr1), Epo, Ncf1 (P47-phox)Ncf1 (P47–phox)
Cia12 (10)8.3D12Rat28-ΔD12Mgh6 (D12Rat19)16,312,646–37,906,549Epo, Ncf1 (P47-phox)Ncf1 (P47-phox)
Cia25 (23)4.7D12Wox12-Nos120,932,556–39,869,383Ncf1 (P47-phox)Ncf1 (P47-phox)
Pia4 (18)8.4ΔD12Mit1 (D12Wox12)-D12Mgh520,932,556–29,130,304Ncf1 (P47-phox)Ncf1 (P47-phox)
Pia4 (12)8.9D12Rat72-D12Rat923,030,712–24,470,522Ncf1 (P47-phox)Ncf1 (P47-phox)
Pia4 (19)53.1D12Wox12-D12Mgh320,932,556–25,271,941Ncf1 (P47-phox)Ncf1 (P47-phox)
Apr1 (20)6.1ΔD12Rat17 (D12Mgh7)-D12Rat2236,834,562–46,043,557Hspb8
Piax* (12)3.3D14Rat32-D14Rat2543,399,833–105,009,477Lif, Osm, Fgfr3
Pia6 (18)4.9D14Mgh3-D14Wox520,165,394–42,600,130GcGc
Ciaa7 (10)3.2D4Rat8-D14Wox1212,400,909–20,178,280GcGc
No name* (15)3D15Mit6-D15Rat2247,302,628–80,370,658Tnfsf11 (Opg1), Htr2aHtr2a
Pia11 (12)4.4D16Rat64-D16Wox859,398,217–88,891,349Gas6
Cia17 (9)4.3D18Mit5-D18Rat8232,458,819–73,666,556Dcc, Adrb2, Slc26a2Adrb2, Slc26a2
Cia26 (23)3.6ΔD18Rat60 (D18Rat13)-ΔD18Mit9 (D18Rat119)66,720,050–80,564,142Dcc
Pia15 (19)3.4D18Mgh3-D18Mit669,013,304–82,920,522Dcc
Cia14* (14)3D19Rat13-D19Mit824,725,553–45,692,656Il15, Nqo1
Aia1 (15)17.9D20Arb2-ΔD20Arb8 (D20Rat33)2,811,409–14,052,767Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb, Nfkbil1Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb, Nfkbil1
Cia1 (8, 14, 15)78.5D20Arb2-ΔD20Arb8 (D20Rat33)2,811,409–14,052,767Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb, Nfkbil1Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb, Nfkbil1
Cia1 (9)9.4D20Wox3-D20Rat603,660,646–14,605,852Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmbTnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb
Pia1 (11)3D20Rat41-D20Rat334,740,610–14,052,767Mif, Tap2, Tap1, Hla-dma, Hla-dmbMif, Tap2, Tap1, Hla-dma, Hla-dmb
Pia1 (19)4.8D20Wox3-D20Rat333,660,646–14,052,767Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmbTnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb
Ciaa1 (9)39.9D20Wox3-D20Rat43,660,646–12,141,740Tnf, Tap2, Tap1, Hla-dma, Hla-dmbTnf, Tap2, Tap1, Hla-dma, Hla-dmb
Ciaa1 (10)5.8ΔD20Mgh4 (0bp)-D20Rat150–20,264,413Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb, Nfkbil1Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb, Nfkbil1
Cia18* (9)3.2DXRat4-ΔDXWox3 (DXRat66)23,494,725–31,245,802
Cia19 (9)4.5DXMgh9-ΔDXWox3 (DXRat66)31,245,802–88,514,169ArAr
  • a An asterisk (∗) denotes a QTL with suggestive but not significant, linkage. Delta (Δ) denotes that the marker is not mapped to the assembly in the current Ensembl database; alternatively, we choose a marker near the target marker for Ensembl searching. The information on the distance between those two markers is from Rat Genome Database (rgd.mcw.edu/maps/); RAA gene: RA-associated gene; RAAP gene, gene containing RA-associated polymorphisms either in coding region or in regulatory region.