Table IV.

Identification of MIF-associated Aga

ProteinTiter < 64Titer 64–256Titer ≥ 512
(n = 11)(n = 17)(n = 10)
Freq.React.Freq.React.bFreq.React.b
CpB0704241630*959**
Cpaf-cc0000730**
Pmp100047820**
CpB0837001016***826**
GroEL231322*834*
OMP2381429***1039*
Pmp6361115936*
PorB0024513*
MOMP4.9d1159717*
Pmp21-cc0057520***
YscL0045510***
CpB05460058513***
MOMP6.2d00514511***
LcrE00713***314
  • a Identification of C. pneumoniae Ags that exhibited significant higher reactivity with sera from donors having C. pneumoniae IgG titer (determined by MIF assay) of 64–256 or ≥512 compared to donors with an IgG titer <64. Frequency (Freq.) indicates the number of reacting sera and reactivity (React.) was calculated as the sum of intensity classes (0–7) for each of the three donor groups, respectively, and given in percent of the maximal reachable value.

  • b *, **, and *** indicate significant differences with p < 0.01, 0.001, and 0.05, respectively.

  • c Cpaf-c and Pmp21-c represent C-terminal parts of the full-length proteins.

  • d MOMP4.9 and MOMP6.2 represent different isoforms (pI 4.9, pI 6.2) of the protein.