Table I.

Mean increases of IgE, IgG1, IgG4, IgA, and IgM levelsa

Bet v 1F1F2P1P2P3P4P5P6
IgET0.400.170.160.010.010.250.010.060.10
F0.220.080.040.000.010.220.000.100.01
P0.030.000.000.000.000.000.000.000.00
IgG1T0.680.420.420.020.050.140.060.160.11
F0.540.430.410.030.040.140.050.230.11
P0.000.010.000.000.000.000.000.000.00
IgG4T0.470.180.230.000.010.020.010.040.04
F0.270.090.100.000.000.000.010.030.02
P0.000.000.000.000.000.000.000.000.00
IgAT0.130.030.120.000.000.000.000.010.01
F0.100.110.030.000.000.000.000.000.00
P0.000.000.000.000.000.000.000.000.00
IgMT0.090.040.110.000.000.030.000.030.01
F0.000.000.000.030.030.010.020.030.00
P0.000.000.000.000.010.000.000.000.00
  • a Ab levels are displayed for patients who received trimer therapy (T), n = 20; fragment therapy (F), n = 13; and placebo (P), n = 27. Statistically significant increases of OD values (time point I—time point III) of >0.050 are marked (p < 0.05).