Table II.

Changes in TCR α-chain expression in backcrossed micea

MouseKI TCR α-Chain ExpressionPercentage Decrease
4 wk8 wk
A
 144.5b17.1>50
 240.120.0>50
 348.217.2>50
 436.116.3>50
B
 539.827.0>25
 638.026.6>25
C
 742.036.0>10
 845.039.0>10
D
 933.933.3None
 1047.348.5None
  • a KI α/Vβ3 TG B10.BR × CBA/Ca F1 male mouse was mated with B10.BR female mice. Offspring were tested for the expression of KI TCR α-chain and Vβ3 TG and the expression of KI TCR α-chain in CD4 T cell population was monitored at 4 and 8 wk of age. Mice were categorized based on the percentage of KI TCR α-chain-positive CD4 T cells.

  • b KI TCR α-chain expression (percent-positive expression in CD4 T cells).