Table I.

FACS analysis of lymphocyte subsets in Klf13+/+ and Klf13−/− micea

Subsets% of Cells
Klf13+/+Klf13−/−
ThymusSP (CD4+)8.01 ± 1.35.9 ± 1.4
SP (CD8+)2.3 ± 0.81.5 ± 0.2
DP (CD4+CD8+)86.6 ± 1.389.9 ± 1.4b
DN (CD4CD8)2.5 ± 1.41.9 ± 0.9
TCRβ38.28 ± 3.725.84 ± 4.29b
BloodT cells (CD3+)30.9 ± 2.729.0 ± 0.55
B cells (B220+)23.7 ± 10.122.2 ± 7.9
NK cells (NK1.1+)7.5 ± 2.65.1 ± 1.0
PeritoneumT cells (CD3+)18.5 ± 6.312.7 ± 2.3
B cells (B220+)31.0 ± 12.035.7 ± 7.6
NK cells (NK1.1+)0.8 ± 0.21.2 ± 0.4
SpleenT cells (CD3+)38.3 ± 4.931.4 ± 11.0
(CD3+CD4+)23.7 ± 4.517.3 ± 3.8
(CD3+CD8+)14.7 ± 0.414.2 ± 7.5
B cells (B220+)39.2 ± 10.236.4 ± 11.0
NK cells (NK1.1+)9.5 ± 3.96.9 ± 2.7
TCRβ34.7 ± 10.030.4 ± 8.5
TCRγδ1.1 ± 0.41.4 ± 0.4
  • a Three pairs of mice were examined at 11–12 wk of age. Values are the mean ± SD. DP, Double positive; DN, double negative.

  • b , p < 0.05.