Table I.

Subsets of the BAL from wild-type mice or IL-17KO mice after BCG infectiona

DaysTotal CellsNeutrophilsMonocytesLymphocytes (×107 cells)
Wild type04.51 ± 0.370.003 ± 0.0094.27 ± 0.180.12 ± 0.12
115.50 ± 4.9910.10 ± 2.113.38 ± 1.271.51 ± 1.38
350.04 ± 14.3923.32 ± 5.8019.48 ± 5.895.88 ± 1.86
533.46 ± 8.803.23 ± 2.2415.29 ± 2.9412.86 ± 2.61
IL-17KO04.53 ± 0.38nd4.29 ± 0.180.18 ± 0.12
13.93 ± 0.56c0.26 ± 0.16c3.35 ± 0.250.25 ± 0.08b
325.97 ± 5.84c12.64 ± 2.05c10.89 ± 2.55c1.94 ± 0.89c
59.66 ± 2.92b0.97 ± 0.38b3.38 ± 1.08c5.07 ± 1.33c
  • a The BAL fluid was recovered at the indicated times after infection with M. bovis BCG. Cells were morphologically examined after staining with May-Grünwald and Giemsa solutions and then counted by microscopy. The values from the IL-17KO mice were significantly different from the values for wild-type mice infected with M. bovisBCG (

  • b p < 0.005;

  • c p < 0.001; nd, not detectable).