Table II.

HLA class I tetramers refolded with various antigenic peptides were tested for binding to different KIR3DL1 transfected cell lines

TetramerPathogen EpitopePeptide SequenceTransfectant Cell Lines
HLABaf3Jurkat
3DL1*0013DL1*0053DL1*0073DL1*01502
A*2402 (Bw4+)A24 p17HIV p17 (28–36)KYKLKHIVW++
A24 nefHIV nef2 (134–141)RYPLTFGW++++
A24 CMVCMV (pp65)QVDPVAALF+
A24 D2Dengue NS3 (D2)INYADRRWCF
B*5703 (Bw4+)B57 KAFHIV p24 (30–40)KAFSPEVIPMF+
B57 A2GHIV p24 (A2G,S4N)KGFNPEVIPMF+
B*0702 (Bw6+)B7 nefHIV nef (128–137)TPGPGVRYPL
B*0801 (Bw6+)B8 EBVEBV (BZLF1)RAKFKQLL
B8 nef Q5HIV nef 5Q (90–97)FLKEQGGL
B*3501 (Bw6+)B35 nefHIV B35 nef (75–82)VPLRPMTY