Table III.

Incidence of arthritis in the partial-advanced intercrossa

GenotypeIncidence (%)c
Cia9 D1Mit270bCia2 HcbDay 35Day 49Day 58Day 70Maximum Arthritic Scorec
aa000205
ab423153060
ah016122830
ba00472
bb534405252
bh14394
ha01281629
hb326293545
hh215323437
  • a Incidence of arthritis at 35, 49, 58, and 70 days, respectively, after disease induction. The backcross mice are grouped based on their genotype of Cia9, given by the marker D1Mit270, in combination with the genotype at Cia2, given by the marker in the Hc gene.

  • b Genotypes given as a, NOD.Q homozygous; b, B10.Q homozygous; h, heterozygous.

  • c Incidence of arthritis at 35, 49, 58, and 70 days, respectively, after immunization of CII.

  • d Maximum arthritic score from day of immunization until end of experiment at day 70.