Table V.

FcγRIIa and FcγRIIIb polymorphisms in 40 C2D patients

Severity of InfectionsFcγRIIa AllotypesaFcγRIIIb Allotypesa
HHHRRRNA1/1NA1/2NA2/2
Group 1 (n = 10)352217
Group 2 (n = 6)231024
Group 3 (n = 11)272038
Group 4 (n = 13)373193
Total (n = 40)25.0%55.0%20.0%7.5%37.5%55.0%
Controls (n = 200)b22.5%51.5%26.0%11.5%47.0%41.5%
  • a No correlation was found between severity of infections (see Table I) and FcγR polymorphisms.

  • b Healthy blood donors.