Table I.

Baseline respiratory parameters in naive male and female C57BL/6 mice assessed using noninvasive whole-body plethysmographya

GendernfVtMVPIFPEF
Male21492 ± 150.23 ± 0.01110.2 ± 7.78.2 ± 0.65.3 ± 0.4
Female20509 ± 130.22 ± 0.01107.6 ± 6.08.2 ± 0.55.2 ± 0.3
  • a Abbreviations: n, Number of mice; f, breathing frequency (breaths/minute); Vt, tidal volume (milliliters/breath); MV, minute ventilation (milliliters/minute); PIF, peak inspiratory flow (milliliters/second); PEF, peak expiratory flow (milliliters/second).