Table III.

Summary of differentially expressed genes within QTL support intervalsa

QTLGenePosition (Mb)DescriptionDay 0Day 10Day 35Day 95
Cia2Glo135.1Glyoxalase 1UpUpUpUp
Stom35.1StomatinUp
Ggta135.2Glycoprotein galactosyltransferase α1, 3UpUpUpDown
Cia27Tpen1120.6Two pore channel 1Up
Oas1a121.12′,5′-oligoadenylate synthetase 1ADown
Ptpn11121.3Protein tyrosine phosphatase nonreceptor type 11Up
Trmq3Rasgrp1116.7RAS guanyl releasing protein 1Up
Thbs1117.6Thrombospondin 1UpDown
1810008K03Rik118.1RIKEN cDNA 1810008K03 geneUpUp
1500003O03Rik119.1RIKEN cDNA 1500003O03 geneUpUpUpDown
Ltk119.1Leukocyte tyrosine kinaseDown
Mga119.4MAX gene associatedDownDown
Ubr1120.3Ubiquitin protein ligase E3 component n-recognin 1Up
Sdh1121.7Sorbitol dehydrogenase 1DownDownDownDown
pldn122.2PallidinUpUp
Sema6d124.1Semaphorin 6DUpDown
Scl27a2126.1Solute carrier family 27, member 2Down
Hdc126.1Histidine decarboxylaseDown
  • a Data were analyzed using dCHIP software, and only the genes expressed differentially in LN between DBA/1 and FVB/N strains in one or more phase of CIA (E/B > 2 or B/E > 2, E − B > 100 or B − E > 100; p < 0.05) are presented: —, Not differentially expressed; Up, with higher expression in DBA/1 strain; Down, with lower expression in DBA/1 strain. The physical positions and description of genes were retrieved from 〈www.ensembl.org〉.