Table III.

Induction of pro- and anti-inflammatory gene expression in macrophages stimulated by Ft LVS LPSa

GeneTreatment
Ft LVS LPSEc LPS
0.1–100 ng/ml1000 ng/ml10,000 ng/ml0.1 ng/ml10 ng/ml
ProinflammatoryTNF-α112026220
IL-12 p35135219419,265
IL-12 p401214764,145
IL-1β1613530618,120
IL-6132818952,583
IFNIFN-β11218834
IFN-γN.D.N.D.N.D.261
ChemokinesIP-10132726112,654
KC1243161870
MCP-11123119
RANTES125241,324
Anti-inflammatoryIL-41112117
OthersiNOS122103,144
  • a Results represent the relative gene expression (fold-induction) above levels present in medium-treated macrophages for the indicated pro- and anti-inflammatory genes 3 h following treatment of macrophages with Ft LVS LPS or E. coli (Ec) LPS. Data were derived from a representative experiment (n = 7).