Table I.

Neutralization of SARS pseudoviruses by anti-RBD mAbs

GroupmAbInhibition of ACE2 BindingND50 of Pseudovirus (μg/ml)
Tor2GD03SZ3
Conf I9F76.220.15>50
12B114.560.7>50
29G23.240.16>50
Conf II26A42.850.49>50
27C11.470.06>50
31H120.210.02>50
Conf III11E 12+1.283.91>50
18D9+0.035.29>50
Conf IV28D6+0.210.160.64
30F9+0.020.080.21
35B5+0.090.060.35
Conf V24F4+0.053.610.14
33G4+0.010.020.01
38D4+0.3535.140.36
Conf VI13B61.321.51.25
19B20.760.620.41
Linear4D5>50>50>50
17H9>50>50>50