Table IV.

Patients with recurrence after ≥2 courses of immunization

CourseIntensity/% Cells PositiveELISPOT (per 105 PBMC)Tetramer (% of CD8+)
gp100MART1TyrosinaseMHC1
Arm1(qw)43/>50%0/00/00/0422.01
42/>50%2/>50%0/01/<5%122.21
20/00/02/>50%3/>50%40.29
23/>50%1/>50%3/>50%1/>50%00
22/>50%3/>50%3/>50%1/<5%00
41/5–50%3/>50%3/>50%0/060616.70
43/>50%3/>50%3/>50%2/>50%1600
43/>50%3/>50%2>50%2/5–50%30315.2
Arm2/(q3w)40/00/00/03/>50%2452.56
41/5–50%0/03/>50%2/>50%240.51
40/01/>50%0/03/>50%22816.85
43/>50%3/>50%3/>50%3/>50%90.47
40/03/>50%3/>50%3/>50%00
Arm3(qdx4)43/5–50%1/>50%3>50%3>50%1140.5
42/>50%n.d.0/00/01513.89
20/00/00/03/<5%160.01