Table I.

Infiltrating leukocytes in leukopenic micea

Neutrophils (×106 cells/cavity)Macrophages (×106 cells/cavity)
LysM:Stat3+/+LysM:Stat3flox/−LysM:Stat3+/+LysM:Stat3flox/−
Control9.1 ± 1.219.6 ± 2.12.9 ± 0.35.5 ± 0.9
Leukopenic1.6 ± 0.3c1.0 ± 0.4c0.7 ± 0.2c0.9 ± 0.4b
  • a Peripheral leukocytes were depleted with cyclophosphamide, as described in the text. The leukopenic mice and vehicle-treated control mice were injected i.p. with thioglycollate. After 4 h, the number of infiltrating leukocytes was counted (six to eight mice, each).

  • b , p < 0.001,

  • c , p < 0.0001, vs control mice.