Table I.

Summary of phenotypic changes in tetramer+ CD8 memory T cells

Tet+a %FSC (MFI)CD25 % (MFI)bCD69 %CD45RA %CD45RO %CCR7 % (MFI)CD62L %
Patient 1
 No stimc1.6(325)0 (5)0.888.567.80.1 (6)0.2
 Stim4.2(491)98.2 (234)77.351.599.714.8 (25)3.5
 Stim + TGF-β15.4(456)85.9 (156)72.639.999.179.1 (52)2
Patient 2
 No stim1.6(317)0.3 (5)5.799.4391.5 (13)1.4
 Stim2.4(464)98.1 (426)56.348.699.78.9 (30)3.1
 Stim + TGF-β13.8(416)54.1 (106)49.755.799.626.4 (38)0.7
Patient 3
 No stim0.5(306)0.8 (6)51.397.691.66.0 (12)2.9
 Stim2.1(466)100 (1352)42.420.399.577.1 (179)2.8
 Stim + TGF-β13.2(477)99.9 (1347)48.620.499.899.1 (373)2.3
  • a Percent tetramer+ cells in CD8+ population.

  • b Percent tetramer+ cells expressing surface marker; MFI is for the entire tetramer+ population.

  • c Stim, stimulation.