Table I.

Evolution toward disease in macaques infected with the pathogenic SIVmac251 strain

Clinical Signs (dpi)aCD4 T Cell Countb (% loss)Viral Loadb (copies/ml)Progressor Status
0300No sign (500)500 (10)10Slow
0191No sign (380)340 (35)1,745Slow
0312No sign (380)570 (20)600Slow
0341No sign (380)1400 (30)1,500Slow
94870No sign (380)420 (20)1,900Slow
R97087Wasting syndrome (killed at 398)60 (90)29,500Moderate
94852Wasting syndrome (killed at 398)50 (92)83,500Moderate
94856No sign (320)245 (50)16,400Moderate
94746Wasting syndrome (killed at 600)110 (80)48,400Moderate
94860No sign (280)320 (55)300,000Moderate
  • (dpi: days post-infection; a,b: CD4 T cell counts and viral loads were determined at the dpi)

  • a dpi, Days postinfection.

  • b CD4 T cell counts and viral loads were determined at the dpi.