Table I.

B cell content of peripheral blood and lymphoid organs of NeuT and NeuT-μMT micea

Lymphocyte OriginNeuTNeuT-μMT
Ab-negativeAb-positive
Peripheral blood50.0 ± 5.10.5 ± 0.21.4 ± 0.5
Spleen45.5 ± 2.52.2 ± 0.35.0 ± 0.4b
Mesenteric lymph node29.5 ± 3.30.5 ± 0.10.6 ± 0.2
Inguinal lymph node26.2 ± 3.70.5 ± 0.20.6 ± 0.3
Peyer patches60.7 ± 1.214.5 ± 1.525.2 ± 1.2b
  • a The percentage of B220-positive cells, evaluated by FACS analysis of gated lymphocytes, is expressed as the mean ± SEM of three to five mice per group.

  • b Significantly different from Ab-negative NeuT-μMT (p < 0.05, Student’s t test).