Table I.

Clonal composition of TIL

Total Number of TRBV Sequences AnalyzedNumber of Distinct Clonal SequencesaNumber of Clonotypes Represented in TIL at:
<5%5–9%10–20%>20%
Responder
 61184137130
 9128104222
 10922017003
 16642016202
 17812421021
 19783832420
 21913732230
 25813935310
 26843732311
 28781512102
 30813733031
 31751813401
 34802119101
Nonresponder
 7803431201
 118243001
 12897878000
 13702218121
 148531011
 15671410211
 18612217311
 20863432011
 22811510122
 24852319112
 27732623111
 29782117112
  • a Clonotypes present within TIL samples were identified by comparison of the TRBV, D, and J region sequences of cDNA clones that were derived from individual TRBV genes.