Table I.

IREM-2 expression on normal populations of PB and BM hemopoietic cellsa

Adult Healthy Individuals
Bone marrow (n = 7)Peripheral blood (n = 4)
Hematopoietic precursors
 Erythroid precursorsNegative
 Myeloid precursorsNegative
 CD34 B cell precursorsNegative
 CD34+ B cell precursorsNegative
Mature cells
 B lymphocytesNegativeNegative
 T/NK lymphocytesNegativeNegative
 NeutrophilsNegativeNegative
 Mast cellsNegative
 EosinophilsNegativeNegative
 BasophilsNegativeNegative
Lymphoplasmocytoid DCsbNegativeNegative
 CD16+ DCs80 ± 6%100%
(74–85%) 82%
 Myeloid DCs100%
 Monocytes43 ± 12%100%
(26–59%) 48%
  • a Results expressed as mean ± SD (range) and median percentage of IREM-2+ cells.

  • b DCs, Dendritic cells.