Table I.

Natural peptides with AI4-preferred TCR contact residuesa

Peptide SequencePeptide AbbreviationAccession No.Protein Source(s)
HEAESYMYLHL9Q60755Calcitonin receptor precursor
FQDENYLYLFNL9P54265DMK
Q7TT50MRCK β
FTDESYLELFSL9P56960Polymyositis/Scleroderma autoantigen 2
RLFENYIELRIL9Q9D4H1Exocyst complex component Sec5
QYLENYLWMQM9P97871Aquarius
TNKENYTELTL9Q8C6H8Stromal cell-derived factor receptor 1
EVVESYMYLEL9Q8K2N2Similar to 1,2-α-mannosidase IC (fragment)
RTSENYLELRLL9Q80TB9MKIAA1569 protein
VMLENYTHLVML9Q8C1H3Similar to Kruppel-associated box zinc finger protein
DMHENYMEMDM9Q8BS74X-linked lymphocyte-regulated complex
VTLENYTHLVTL9AAH53084Hypothetical protein
YFIENYLELMimOriginal AI4 mimotope
YAIENYLELMimA2A2-substituted AI4 mimotope
  • a This list contains the results of a ScanProsite search of Swiss-Prot and TrEMBL protein databases, limited to the taxon Mus musculus, for peptides with the AI4-preferred pattern X-X-X-E-[NS]-Y-[ILMTV]-[EHWY]-[LM], in which X represents any amino acid.