Table I.

Genes with altered expression in both CD4+CD25+ T cells and primed CD4+ T cells in response to IL-2 stimulationa

Gene NameAccession No.Average Fold Changeb
CD4+CD25+Primed CD4+
c-Myc L0003911.32.3
IL-2R α-chain (CD25)M262719.87.0
TNFM168198.614.9
SOCS-2 U883278.04.0
ESTAW0466948.03.7
Smfn (small fragment nuclease)AI8398824.93.5
Cytokine-inducible SH2-containing protein D896134.63.3
SOCS-1 U883254.35.3
Bcl-2 L315324.02.3
Xbp-1AW1238803.57.5
ReticulocalbinD130032.93.3
Agpat3 (1-acylglycerol-3-phosphate-O-acyltransferase 3)AW1242012.12.5
Zinc finger proteinAV371846−2.5−3.0
IL-7RM29697−2.8−6.1
α-ActininJ04181−3.0−3.0
  • a Genes previously characterized as being induced by STAT5-mediated signaling are italicized.

  • b Mean fold alteration in expression for each gene is calculated from two independent experiments for both CD4+CD25+ T cells and primed CD4+ T cells.