Table I.

Combined absolute number data from all day 20 experiments performed^a

Expt.	Experimental Conditions				No. of CD4 Cells Expressing Thy1.1 (×10⁻³)
Expt.	Transferred cell no. (×10⁻⁶)	Peptide dose (μg)	LPS dose (μg)	CD40 dose (μg)	Inguinal LN	Axillary LN	Brachial LN	Mesenteric LN	Spleen	Liver	Lung
1	2.0	—	—	—	0.69	0.43	0.95	2.86	15.13	1.23	0.04
	2.0	—	50	—	1.42	1.10	1.64	2.70	37.20	1.17	0.35
	2.0	100	—	—	0.39	0.13	0.29	0.83	<4.73	0.63	0.06
	2.0	100	—	250	<0.40	0.34	0.45	0.44	6.89	0.50	0.10
	2.0	100	50	—	3.88	2.52	4.07	31.58	406.85	23.06	10.65
	2.0	100	50	250	ND^b	ND	ND	ND	ND	ND	ND
	2.0	100	75	250	0.50	0.32	0.28	1.50	22.91	1.53	0.07
2	2.0	—	—	—	<0.18	<0.08	<0.16	<0.18	<6.47	<0.42	<0.04
	2.0	—	25	250	0.60	0.29	0.36	7.68	30.39	1.21	0.13
	2.0	100	—	—	<0.24	<0.11	<0.25	<0.26	6.78	<0.72	<0.06
	2.0	100	—	250	<0.40	<0.10	<0.21	<0.31	<10.36	<0.33	<0.12
	2.0	100	25	—	3.26	2.30	2.40	8.86	175.46	5.15	1.45
	2.0	100	25	250	ND	ND	ND	ND	ND	ND	ND
3	2.0	100	—	—	0.26	0.40	0.13	0.99	17.58	2.15	0.34
	2.0	100	—	250	<0.37	<0.30	<0.36	<0.27	<8.76	<0.50	<0.09
	2.0	100	10	—	0.24	0.28	0.19	0.62	65.15	5.02	2.29
	2.0	100	10	250	ND	ND	ND	ND	ND	ND	ND
4	0.5	—	—	—	0.32	<0.18	<0.21	0.08	8.02	0.58	0.14
	0.5	—	10	250	0.52	0.53	0.11	0.72	36.41	<0.56	0.27
	0.5	100	—	—	0.27	0.18	<0.21	0.25	19.11	0.68	0.17
	0.5	100	—	250	0.47	0.15	0.34	0.17	27.35	0.96	0.10
	0.5	100	10	—	0.18	0.18	0.28	0.66	69.75	6.45	0.41
	0.5	100	10	250	2.73	1.72	1.02	8.93	613.71	59.21	5.18
5	0.5	—	—	—	<0.31	<0.15	<0.36	<0.67	<5.82	<0.57	<0.12
	0.5	—	10	250	<0.30	<0.28	<0.33	0.50	8.06	0.59	<0.25
	0.5	100	—	—	0.16	<0.18	<0.18	0.29	4.35	0.72	0.11
	0.5	100	—	250	0.38	<0.23	<0.23	<0.45	6.70	0.62	0.17
	0.5	100	10	—	0.47	0.26	0.29	0.31	25.74	1.77	0.57
	0.5	100	10	250	0.42	0.41	0.13	3.74	37.15	1.31	0.32
6	0.5	—	—	—	0.22	<0.12	<0.23	0.57	<8.42	<0.63	<0.09
	0.5	—	10	250	0.39	0.06	0.14	0.22	7.87	0.46	0.21
	0.5	100	—	—	<0.15	<0.12	<0.27	<0.76	6.20	0.70	<0.12
	0.5	100	—	250	<0.14	<0.04	<0.18	<0.70	<7.44	<0.47	<0.05
	0.5	100	10	—	<0.33	<0.14	<0.16	<0.62	<5.44	0.49	0.09
	0.5	100	10	250	1.50	0.30	0.97	13.40	272.54	12.56	2.67

a Listed are the number of cells adoptively transferred and the doses of peptide, anti-CD40 mAb, and LPS injected. Results list the number (×10⁻³) of CD4⁺Thy1.1⁺ cells present in each tissue examined from six separate experiments. Numbers were obtained as described in the legend to Fig. 8⇑b.
b ND, No data was obtained.