Table I.

Increased deposits of IgA, but not of IgG, in the glomeruli of (NZW × B6) F1-hbcl-2 Tg micea

MiceIgMIgGIgA
B6 non-Tg
B6-hbcl-2 Tg
NZW++
(NZB × NZW)F1++++++ND
(NZW × B6)F1 non-Tg++
(NZW × B6)F1-hbcl-2 Tg++++++
  • a The presence of glomerular IgM, IgG, and IgA deposits in the different strain of mice (n = 3 mice/group) was evaluated by immunofluorescence on kidney cryosections at 6 mo of age. The intensity of fluorescence is indicated (0 to +++). ND, not done.