Genotype | Number of Mice | Mean Age (wk) | Thymus | ||||||
---|---|---|---|---|---|---|---|---|---|

Cell number | DN (%) | DP (%) | SP CD8^{+} (%) | Calculated total number DN | Calculated total number DP | Calculated total number SP CD8^{+} | |||

+/+ | 7 | 7.00 | 103.7 ± 42.3 | 8.1 ± 4.0 | 66.8 ± 8.1 | 18.7 ± 9.5 | 8.0 ± 3.6 | 70.8 ± 35.4 | 18.9 ± 11.6 |

−/− | 7 | 6.71 | 32.1 ± 15.2 | 35.9 ± 13.7 | 31.9 ± 15.7 | 23.6 ± 7.6 | 11.1 ± 7.0 | 10.9 ± 9.8 | 7.0 ± 2.5 |

p = 0.004 | p = 0.001 | p = 0.001 | p = 0.310 | p = 0.330 | p = 0.005 | p = 0.038 |

a All numbers are shown as mean ± SD. DN, CD4/CD8 DN thymocytes; DP, CD4/CD8 DP thymocytes; SP, CD8 SP thymocytes.