Table I.

Disease phenotypes in mutant and control strains

GenotypeNo. Positive/Total Dissected
Days 75–99Days 100–120Day >120
B6NDa0/30/11
B6.kdb1/1113/1934/37
CD4−/−kd/kd1/41/422/26
CD8−/−kd/kdND8/1013/17
CD28−/−kd/kdND3/1941/62
IL-2−/−kd/kd4/92/2ND
Rag-1−/−kd/kd4/87/721/27
ICAM-1−/−kd/kd0/21/223/23
β2m−/−kd/kd0/22/28/15
  • a ND, Not done.

  • b The B6.kd mice in this table were from at least the eighth generation of backcrossing.