Table I.

Phenotypic analysis of IDO+ cells from CTLA4-Ig-treated F1 (CBA × B6) mice

PhenotypeCell TypeIDO+ (%)a
Sort 1
CD11c+ and/or CD11b+Myeloidhtb
CD11cCD11bNonmyeloid0
Sort 2
CD11c+B220CD8α+CD8 + DCs100
CD11c+B220CD8αCD8− DCs0
Sort 3
B220+CD11c+CD19pDCsc100
B220+CD11cCD19+B cells0
B220CD11cCD190
Sort 4
DX5+CD11c+CD8α+NK DCs100
DX5+CD11c+CD8αNK DCs∼60
DX5+CD11cNK cells0
  • a Percent of cells stained intensely with anti-IDO Ab.

  • b Heterogeneous expression on <50% of cells.

  • c Plasmacytoid DCs.