Table V.

Effect of IL-17 neutralization on abscess formation in vivo

TreatmentaNo. of Animals with Abscess/Total (%)bp Valuec
Control IgG9/10 (90)
Anti-IL-17 Ab1/10 (10)0.001
  • a Animals received 100 μg of affinity-purified rabbit Ab via the i.p. route at the time of challenge.

  • b Animals challenged via the i.p. route with 1 × 108 CFU of B. fragilis and SCC.

  • c Compared with animals that received control IgG Ab.