Effect of IL-17 neutralization on abscess formation in vivo
Treatmenta | No. of Animals with Abscess/Total (%)b | p Valuec |
---|---|---|
Control IgG | 9/10 (90) | |
Anti-IL-17 Ab | 1/10 (10) | 0.001 |
a Animals received 100 μg of affinity-purified rabbit Ab via the i.p. route at the time of challenge.
b Animals challenged via the i.p. route with 1 × 108 CFU of B. fragilis and SCC.
c Compared with animals that received control IgG Ab.