CD4+ T cells from STAT6−/− mice transfer abscess induction
| Donor | Recipienta | No. of Animals with Abscess/Total (%)b | p Valuec |
|---|---|---|---|
| Wild type | αβTCR−/− | 7/9 (78) | |
| STAT4−/− | αβTCR−/− | 2/12 (17) | 0.009 |
| STAT6−/− | αβTCR−/− | 9/10 (90) | NS |
a Recipient animals received 3 × 106 CD4+ T cells from donor animals via the intracardiac route 24 h prior to challenge.
b Animals challenged via the i.p. route with 1 × 108 CFU of B. fragilis and SCC.
c Compared with animals that received T cells from wild-type animals.