Functional categorization of known antigens identified by SEREX from HCC cDNA expression libraries
Functional Category | No. | Examples |
---|---|---|
Enzyme | 12 | Peroxisomal enoyl-coenzyme isomerase, ATP synthase, V-ATPase GST, disulfide isomerase, topoisomerase IIb |
Signal transduction | 2 | Translocation three four for small G protein, TFDP1 protein |
Metabolic protein | 10 | Ferritin L chain, apolipoproteins II and E |
Cytoskeleton protein | 1 | Actin-like protein |
DNA/RNA duplication and regulation | 5 | Transcription elongation factor, RNA transcription mediator, snRNA-associated sm-like protein, TATA element modulator |
Growth factor- and receptor-inducing gene products | 3 | IFN-inducible gene, insulin-induced gene Pleiotrophic regulator I |
Ag processing | Dna J protein (heat shock protein) | |
Tumor suppressor gene | 1 | Tumorous imaginal discs protein |
Complement molecules | 3 | H factor 1, factor H homolog, factor H1-related protein |
Ectopic expression | 2 | Human obese gene, Ig rearranged γ-chain V-D-J |