Functional categorization of known antigens identified by SEREX from HCC cDNA expression libraries
| Functional Category | No. | Examples |
|---|---|---|
| Enzyme | 12 | Peroxisomal enoyl-coenzyme isomerase, ATP synthase, V-ATPase GST, disulfide isomerase, topoisomerase IIb |
| Signal transduction | 2 | Translocation three four for small G protein, TFDP1 protein |
| Metabolic protein | 10 | Ferritin L chain, apolipoproteins II and E |
| Cytoskeleton protein | 1 | Actin-like protein |
| DNA/RNA duplication and regulation | 5 | Transcription elongation factor, RNA transcription mediator, snRNA-associated sm-like protein, TATA element modulator |
| Growth factor- and receptor-inducing gene products | 3 | IFN-inducible gene, insulin-induced gene Pleiotrophic regulator I |
| Ag processing | Dna J protein (heat shock protein) | |
| Tumor suppressor gene | 1 | Tumorous imaginal discs protein |
| Complement molecules | 3 | H factor 1, factor H homolog, factor H1-related protein |
| Ectopic expression | 2 | Human obese gene, Ig rearranged γ-chain V-D-J |