Table I.

P-selectin expression over disease course in EAEa

TissueControl2 Days Pre4 Days Post2 wk Post
Skin0.106 ± 0.02700.190 ± 0.06630.133 ± 0.04030.144 ± 0.0403
Muscle0.052 ± 0.01870.113 ± 0.04510.056 ± 0.01540.026 ± 0.0324
Lung0.115 ± 0.06400.083 ± 0.04770.059 ± 0.03010.048 ± 0.0241
Heart0.005 ± 0.00500.025 ± 0.02450.015 ± 0.00940.020 ± 0.0100
Liver0.037 ± 0.02670.326 ± 0.1221**0.002 ± 0.00180.030 ± 0.0304
Pancreas0.051 ± 0.01060.148 ± 0.0306**0.070 ± 0.01830.074 ± 0.0139
Spleen0.191 ± 0.07310.709 ± 0.0984**0.454 ± 0.06420.396 ± 0.1111
Mesentery0.018 ± 0.01030.180 ± 0.0262**0.092 ± 0.03250.096 ± 0.0210
Stomach0.072 ± 0.01510.163 ± 0.0272b0.096 ± 0.01270.087 ± 0.0220
Small bowel0.103 ± 0.01610.142 ± 0.03340.125 ± 0.03940.096 ± 0.0206
Large bowel0.036 ± 0.00870.048 ± 0.01590.030 ± 0.01370.065 ± 0.0223
Bone marrow0.378 ± 0.01130.368 ± 0.02570.393 ± 0.03650.588 ± 0.0486**
  • a Control, 2 wk post, n = 5; 3 days pre, n = 4; 4 days post, n = 6.

  • b , p < 0.05 vs control.

  • c ∗, p < 0.01 vs control.