Table I.

Effect of viruses and poly(I:C) on donor and host CD8 T cell numbera

DonorHost
No. of cells × 105Fold increaseNo. of cells × 105Fold increase
Spleen
No virus1.4 ± 0.481 ± 21
Poly(I:C)1.45 ± 0.61.0483 ± 211.03
LCMV350 ± 25034489 ± 501.1
PV52 ± 1351145 ± 471.8
VV5.2 ± 0.35.2279 ± 1463.4
PEC
No virus0.03 ± 0.020.35 ± 0.13
Poly(I:C)0.26.62.98
LCMV16.6 ± 185024.3 ± 2.212.3
PV14 ± 1342055 ± 14.7157
VV1.8 ± 1.653.284 ± 32239
  • a Using the same strategies described in Fig. 1, the total numbers of donor and host CD8 T cells were calculated by multiplying their percentages with the total leukocyte numbers. At least three mice from each group were used in calculations. Fold increases over the “no virus” control values were calculated based on the absolute numbers.