Table I.

Expression levels of genes encoding proteins that distinguish among lymphocyte subsets or activation state

Population Expression LevelControlSLERAInsulin-Dependent Diabetes MellitusMS
Average ± SD
T cell Ags
CD3δ0.7 ± 0.2a0.6 ± 0.40.5 ± 0.20.5 ± 0.20.4 ± 0.2
CD3γ0.5 ± 0.10.6 ± 0.90.4 ± 0.10.3 ± 0.10.4 ± 0.1
CD8β (Tc)0.8 ± 0.30.8 ± 0.20.6 ± 0.20.5 ± 0.20.5 ± 0.2
CD44 (memory)0.5 ± 0.10.8 ± 0.50.7 ± 0.40.8 ± 0.50.7 ± 0.4
CD69 (activation)0.5 ± 0.20.7 ± 0.30.6 ± 0.20.8 ± 0.30.7 ± 0.4
CD62 (L-selectin)1.3 ± 0.61.4 ± 0.91.8 ± 1.11.7 ± 1.11.9 ± 1.1
CD122 (IL-2R β)0.4 ± 0.10.4 ± 0.20.5 ± 0.20.3 ± 0.10.3 ± 0.1
B cell Ags
CD79a0.6 ± 0.30.4 ± 0.20.4 ± 0.20.4 ± 0.20.4 ± 0.2
CD79b0.5 ± 0.20.6 ± 0.30.8 ± 0.70.8 ± 0.40.7 ± 0.3
CD720.4 ± 0.10.4 ± 0.30.4 ± 0.20.3 ± 0.10.3 ± 0.1
CD220.3 ± 0.10.4 ± 0.30.4 ± 0.40.3 ± 0.10.3 ± 0.1
Monocyte Ags
CD140.5 ± 0.20.4 ± 0.20.3 ± 0.10.3 ± 0.20.3 ± 0.2
CD1630.3 ± 0.10.4 ± 0.20.4 ± 0.20.3 ± 0.10.3 ± 0.2
CD32 (B/mθ)0.3 ± 0.10.5 ± 0.40.5 ± 0.30.3 ± 0.10.4 ± 0.2
Activation-induced Ags
CD54 (ICAM-1)4.4 ± 1.83.1 ± 2.14.3 ± 0.74.3 ± 2.23.9 ± 1.0
CD380.4 ± 0.30.3 ± 0.20.3 ± 0.10.3 ± 0.10.3 ± 0.1
CD710.2 ± 0.10.2 ± 0.20.2 ± 0.10.2 ± 0.10.2 ± 0.1
  • a Average expression level of the indicated genes within the different populations.